According to a randomized, double blind, placebo controlled clinical trial published in Elsevier journal Research in Autism Spectrum Disorders (2013), l carnitine supplementation demonstrated a significant therapeutic benefit in children diagnosed with Unique acyl carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder Translational Psychiatry Autism and Biomedical Interventions Above and Beyond Therapy JCI Increasing histone acetylation improves sociability and restores learning and memory in KAT6B haploinsufficient mice Acetyl l carnitine alleviates valproate induced autism like behaviors through attenuation of hippocampal mitochondrial dysregulation ScienceDirect Targeting Skeletal Muscle Dysfunction With L Carnitine for the Treatment of Patients With Chronic Obstructive Pulmonary Disease In Vivo