Dihexa is an experimental cognitive peptide that may help the brain build stronger connections between neurons instead of just temporarily boosting neurotransmitters like many nootropics do. It works through the HGF c Met pathway, HGF c Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR NGF axis Cell Death & Disease Frontiers HGF and MET: From Brain Development to Neurological Disorders Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted HGF c Met 1 integrin signalling axis induces tunneling nanotubes in A549 lung adenocarcinoma cells Life Science Alliance An overview of the c MET signaling pathway Shawna Leslie Organ, Ming Sound Tsao, 2011