Increase in renal glutathione in cholestatic liver disease is due to a direct effect of bile acids American Journal of Physiology Renal Physiology American Physiological Society WhyScience #Day33: Genome wide studies have uncovered >1,000 loci linked to kidney function, but pinpointing causal genes remains a hurdle. In our new @SciTransMed paper, we integrated human multi omics and mouse models to Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells ScienceDirect Full article: Glutathione metabolism rewiring protects renal tubule cells against cisplatin induced apoptosis and ferroptosis Understanding Glutathione: Benefits, Safety, and Misconceptions Cysteine as a Multifaceted Player in Kidney, the Cysteine Related Thiolome and Its Implications for Precision Medicine