If you have MTHFR , or think you might , this is the most important connection in this series. MTHFR is a gene mutation that impairs methylation. And methylation is the What You Need to Know About Methylation & the MTHFR Gene Mutation Taylor Dukes Wellness Is The MTHFR Gene Affecting Your Health? OC Integrative Medicine What is the MTHFR Gene Mutation? MTHFR Diet & Supplements: What to Eat, Avoid & Best Choices Glutathione: The Most Powerful Antioxidant