Labial Macules: Dark Spots on the Lip Dermatology Advisor Labial melanotic macule Stock Image C057 2077 Science Photo Library Oral melanotic macules are harmless but can be removed easily with laser treatment! Quick, safe, and effective. Say hello to even toned lips! #laser #candela #pico #lips #face #makeup #spa Citalopram Induced Oral Melanotic Macules in a Female Patient and a Review of the Literature Cureus Lip pigmentation This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.