Man Concerned About a New Spot On His Lip Let's Diagnose VisualDx 40 F. 4 mm dark brown macule on lower lip. Diagnosis? Digital slide: https: kikoxp.com posts 8019. Answer https: www.youtube.com watch?v=O2yi2ir0Ubg #pathology #pathologists #pathTwitter #dermpath #dermatology #dermatologia #dermtwitter Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Smoker's melanosis Wikipedia Dark Spot on Lip: Harmless or Serious? What to Check First La Bouche Parfaite